Title:
drugs for treating Tb infection and Alzheimer’s disease
Speaker:
Huilin Li
Subject:
Tb infection, Alzheimer’s disease
Area:
Biochemistry
Type of school:
School name:
Brookhaven
Country:
United States
Course language:
English (United States)
Course media:
Video
Course duration:
Contributor:
jakob sandvad
Comments:
417th Brookhaven Lecture by Huilin Li (59 min.)
Proteins that cleave other proteins using a molecule of water, protease complexes are exquisite macromolecular machines involved in a multitude of physiological and cellular reactions. Our structural studies shed light into the inner workings of multi-protein assemblies, and they reveal a surprisingly common strategy for controlled proteolysis employed by the two drastically different machines. Further research will facilitate rational design of drugs for treating Tb infection and Alzheimer’s disease. September 20, 2006